Close Menu

    Subscribe to Updates

    Get the latest creative news from FooBar about art, design and business.

    What's Hot

    In win for Trump, House narrowly OKs effort to claw back $9B from budget — including cuts to public broadcasting and USAID

    July 18, 2025

    Evaluating generative AI models with Amazon Nova LLM-as-a-Judge on Amazon SageMaker AI

    July 18, 2025

    Model predicts long-term effects of nuclear waste on underground disposal systems | MIT News

    July 18, 2025
    Facebook X (Twitter) Instagram
    • Demos
    • Buy Now
    Facebook X (Twitter) Instagram YouTube
    14 Trends14 Trends
    Demo
    • Home
    • Features
      • View All On Demos
    • Buy Now
    14 Trends14 Trends
    Home » Extended surgery could help lower risk of second cancer in patients with genetic condition: Study, ET HealthWorld
    Healthcare

    Extended surgery could help lower risk of second cancer in patients with genetic condition: Study, ET HealthWorld

    adminBy adminApril 28, 2025No Comments2 Mins Read0 Views
    Facebook Twitter Pinterest LinkedIn Telegram Tumblr Email
    Share
    Facebook Twitter LinkedIn Pinterest Email


    New Delhi: In patients of Lynch syndrome — an inherited condition — risk of developing a second tumour could be lower among those having an extended resection, involving a removal of organs and tissues adjacent to the affected ones, compared to segmental resection, according to a study. The inherited condition increases one’s risk of cancer, especially that of colon and rectum.

    An international collaboration, including researchers from the Institute of Human Genetics, Ahmedabad, compared the incidence of metachronous colorectal cancer — the second cancer develops distinct from and at least six months following diagnosis of the first — after segmental versus extended surgical resection in patients with Lynch syndrome.

    The analysis looked at data taken from the ‘Prospective Lynch Syndrome Database’, involving 8,500 patients from 25 different countries. Findings are published in the British Journal of Surgery.

    Once colon cancer is identified, European and American guidelines recommend considering an extended colorectal surgery for patients of Lynch syndrome carrying the ‘path_MLH1’ and ‘path_MSH2’ gene variants, and a segmental resection for those carrying the ‘path_MSH6’ and ‘path_PMS2’ gene variants.

    All these gene variants are associated with a higher lifetime risk of developing colorectal, gynaecological and urinary tract cancers, among others.

    Overall, a higher risk of metachronous colorectal cancer was found to be higher among patients who underwent segmental resection, compared to those who underwent extended surgery.

    For example, path_MLH1 carriers had a higher risk of metachronous (colorectal cancer) by the age of 75 years after segmental colorectal resection (69.1 per cent), compared with extended surgery (25.1 per cent), the team said.

    “This study has found that path_MLH1 and path_MSH2 carriers who undergo segmental resection for a first colorectal cancer were at increased risk of metachronous colorectal cancer, compared with those with no prior colorectal cancer,” the authors wrote.

    They said the study’s findings contributes to the ongoing discussion on surgical strategies for patients with Lynch syndrome.

    The research team also included members from the US, Europe and Australia.

    • Published On Apr 28, 2025 at 05:37 PM IST

    Join the community of 2M+ industry professionals

    Subscribe to our newsletter to get latest insights & analysis.

    Newsletter icon

    Download ETHealthworld App

    • Get Realtime updates
    • Save your favourite articles






    Scan to download App




    Source link

    Share. Facebook Twitter Pinterest LinkedIn Tumblr Email
    admin
    • Website

    Related Posts

    Mandatory NAT Testing in Blood Banks Urged by Experts to Ensure Safe Blood Supply, ETHealthworld

    July 18, 2025

    Good oral health can reduce cancer risk, improve overall health: AIIMS Delhi study, ETHealthworld

    July 17, 2025

    HC grants bail to businessman Sujit Patkar, ETHealthworld

    July 17, 2025

    Groundbreaking Gene Editing Technique Gives Hope to Families with Genetic Disorders, ETHealthworld

    July 17, 2025

    WCD Ministry alerts states on risks of high edible oil consumption, ETHealthworld

    July 17, 2025

    Private Equity Investment in Indian Healthcare Surges to ₹4,900 Crore in Q2 2025, ETHealthworld

    July 17, 2025
    Leave A Reply Cancel Reply

    Demo
    Top Posts

    ChatGPT’s viral Studio Ghibli-style images highlight AI copyright concerns

    March 28, 20254 Views

    Best Cyber Forensics Software in 2025: Top Tools for Windows Forensics and Beyond

    February 28, 20253 Views

    An ex-politician faces at least 20 years in prison in killing of Las Vegas reporter

    October 16, 20243 Views

    Laws, norms, and ethics for AI in health

    May 1, 20252 Views
    Don't Miss

    In win for Trump, House narrowly OKs effort to claw back $9B from budget — including cuts to public broadcasting and USAID

    July 18, 2025

    In a major win for President Donald Trump, the Republican-led House narrowly passed a White…

    Evaluating generative AI models with Amazon Nova LLM-as-a-Judge on Amazon SageMaker AI

    July 18, 2025

    Model predicts long-term effects of nuclear waste on underground disposal systems | MIT News

    July 18, 2025

    Funders commit $1B toward developing AI tools for frontline workers

    July 18, 2025
    Stay In Touch
    • Facebook
    • Twitter
    • Pinterest
    • Instagram
    • YouTube
    • Vimeo

    Subscribe to Updates

    Get the latest creative news from SmartMag about art & design.

    Demo
    Top Posts

    ChatGPT’s viral Studio Ghibli-style images highlight AI copyright concerns

    March 28, 20254 Views

    Best Cyber Forensics Software in 2025: Top Tools for Windows Forensics and Beyond

    February 28, 20253 Views

    An ex-politician faces at least 20 years in prison in killing of Las Vegas reporter

    October 16, 20243 Views
    Stay In Touch
    • Facebook
    • YouTube
    • TikTok
    • WhatsApp
    • Twitter
    • Instagram
    Latest Reviews
    Demo
    About Us
    About Us

    Your source for the lifestyle news. This demo is crafted specifically to exhibit the use of the theme as a lifestyle site. Visit our main page for more demos.

    We're accepting new partnerships right now.

    Email Us: info@example.com
    Contact: +1-320-0123-451

    Facebook X (Twitter) Pinterest YouTube WhatsApp
    Our Picks

    In win for Trump, House narrowly OKs effort to claw back $9B from budget — including cuts to public broadcasting and USAID

    July 18, 2025

    Evaluating generative AI models with Amazon Nova LLM-as-a-Judge on Amazon SageMaker AI

    July 18, 2025

    Model predicts long-term effects of nuclear waste on underground disposal systems | MIT News

    July 18, 2025
    Most Popular

    ChatGPT’s viral Studio Ghibli-style images highlight AI copyright concerns

    March 28, 20254 Views

    Best Cyber Forensics Software in 2025: Top Tools for Windows Forensics and Beyond

    February 28, 20253 Views

    An ex-politician faces at least 20 years in prison in killing of Las Vegas reporter

    October 16, 20243 Views

    Subscribe to Updates

    Get the latest creative news from FooBar about art, design and business.

    14 Trends
    Facebook X (Twitter) Instagram Pinterest YouTube Dribbble
    • Home
    • Buy Now
    © 2025 ThemeSphere. Designed by ThemeSphere.

    Type above and press Enter to search. Press Esc to cancel.